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Orthopedic Drugs, Implants and Devices

Product Type: Market Research Report

Publication Date: Oct 04, 2004

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SUMMARY

REPORT HIGHLIGHTS

The total orthopaedic drug, implant and device market is expected to reach $44 billion by end of 2004. Rising at an average annual growth rate (AAGR) of 11%, the market is expected to reach $74.1 billion by 2009.
Orthopedic drugs take about three quarters of the market and it is expected to rise at an AAGR of 10.5% reaching $56.2 billion by 2009.
In this category, skeletal muscle relaxants are increasing at a very low AAGR, i.e., 4%, while bone stabilizers and disease modifying agents are rising rapidly at AAGRs of 13.8% and 13.2%, respectively.
Sales in 2003 for implants and devices were $8.7 billion and are expected to rise at an AAGR of 12.5% and reach $17.9 billion by 2009.

Global Sales of Orthopaedic Drugs, Implants,and Devices, 2002-2009

;Source: BCC, Inc.

INTRODUCTION

Much of the pain and disfigurement that accompanies aging is concentrated in the bones and joints. While these disorders rarely are life-threatening, they extract an enormous toll in pain and disability, and affect a large percentage of the population. Not surprisingly, a multibillion dollar industry has grown up to ameliorate these bone and joint disorders.

Although it may not be intuitively obvious, the manufacturer of pain relievers and one that makes knee prostheses are competing for the same dollar. Most pain relievers are sold to arthritis sufferers. Almost no one wants a titanium and plastic knee or shoulder while the flesh and blood version still functions. It is only when the pain reliever quits working that a prosthesis becomes attractive. An even more obscure competition exists between those who make fracture fixation devices and those who supply drugs to prevent osteoporosis. The vast majority of bone fractures that require internal fixation occur in the elderly because the calcium has leached out of their bones. An effective osteoporosis drug would prevent most bone fractures and eliminate most of the market for fracture fixation devices, as well as a large part of the market for allograft bone and bone substitutes.

This BCC report deals with drugs, implants and devices used in orthopaedic industry. It discusses their strengths and weaknesses in light of new technologies, growing competition and changing customer needs.

SCOPE OF STUDY

The report contains:

Analysis of the types of drugs, implants and devices used in orthopaedics
Analysis of each technique with sales estimates and market projections through 2009
A look at manufacturers, new products, and market share information
Discussion of technological issues including the latest trends and developments
Examination of government regulations
Listings of approvals of orthopaedic drugs, devices and implants from 2000-2004
Discussion of patents in the industry and their significance.

METHODOLOGY

A comprehensive literature and patent search was conducted. Literature included technical newsletters and journals, as well as many other sources. Data was collected via interviews with and mail from various analytical, chemical, and pharmaceutical companies. This data was compiled, and the projections were based on such estimates as: the current number of end users, potential end users, likely unit prices, rates of consumption, and market trends.

INFORMATION SOURCES

BCC surveyed many companies to obtain the data for this study. Included were manufacturers and end users of orthopaedic products. Data was gathered from these industries, and officials/physicians were interviewed. Newsletters, company literature, product literature, a host of technical articles, journals, indexes, and abstracts were consulted. Exhaustive investigations of databases by key terminology were done. In addition, data was compiled from current financial and trade information, and government sources.

INTRODUCTION

STUDY OBJECTIVES
REASONS FOR DOING THIS STUDY
CONTRIBUTIONS TO THE STUDY
SCOPE OF THE STUDY
METHODOLOGY
INFORMATION SOURCES
ABOUT THE AUTHOR
BCC ON-LINE SERVICES
DISCLAIMER

SUMMARY

Summary Table:
GLOBAL SALES OF ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, THROUGH 2009 ($ BILLIONS)
Summary Figure:
GLOBAL SALES OF ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, 2002-2009 ($ BILLIONS)

OVERVIEW

WHAT IS ORTHOPAEDICS?
COMMON ORTHOPAEDIC DISORDERS

Table 1 COMMON ORTHOPAEDIC DISORDERS
- SOME OTHER RELATED ORTHOPAEDIC DISORDERS
  - ACHONDROPLASIA
  - ANKLE PAIN
  - ANKLE SPRAINS
  - ARTHRITIS MUTILANS
  - ARTHROGRYPOSIS
  - BONE TUMOR
  - BURSITIS
  - CERVICAL ARTHRITIS
    - Symptoms
    - Treatment
  - DOWAGERS HUMP
  - FIBROUS DYSPLASIA
    - Cause and Symptoms
    - Treatment
      - Nonsurgical Treatments
  - HEEL SPURS
    - Cause and Symptoms
    - Treatment
  - JOINT INFECTIONS
  - JUVENILE ARTHRITIS
    - Causes and Symptoms
  - LUMBAR ARTHRITIS
    - Cause and Symptoms
    - Treatment
  - OSTEOPENIA
  - SAPHO SYNDROME
  - TENDINITIS
    - Treatment
  - VANISHING BONE SYNDROME
- FRACTURES
  - TYPES OF FRACTURES
  - CLASSIFICATION OF FRACTURES
  - TREATMENT FOR FRACTURES
Table 2 TYPES OF TREATMENTS FOR FRACTURES

CLASSIFICATION OF DRUGS BASED ON THERAPEUTIC CATEGORY

ANALGESICS, ANTI-INFLAMMATORIES AND ANTIPYRETICS (NON-OPIOD) (NON-STEROIDAL ANTI-INFLAMMATORY DRUGS, NSAIDs)

Table 3 NON-OPIOID DRUGS USED AS ANALGESICS, ANTI-INFLAMMATORIES, AND ANTIPYRETICS
- OPIOID ANALGESICS
Table 4 OPIOID DRUGS USED AS ANALGESICS
- CORTICOSTEROIDS
Table 5 CLASSIFICATION OF CORTICOSTEROIDS
Table 6 CORTICOSTERIOD DRUGS USED AS ANTI-INFLAMMATORYS
- BONE STABILIZERS
Table 7 DRUGS USED AS BONE STABILIZERS
- SKELETAL MUSCLE RELAXANTS
Table 8 DRUGS USED AS SKELETAL MUSCLE RELAXANTS
- THERAPEUTIC VITAMINS AND MINERALS
Table 9 DRUGS USED AS VITAMIN SUPPLEMENTS
Table 10 DRUGS USED AS CALCIUM SUPPLEMENTS
- ANTIBIOTICS
Table 11 DRUGS USED AS ANTIBIOTICS
Table 11 (CONTINUED)
Table 11 (CONTINUED)
- DISEASE-MODIFYING AGENTS
Table 12 DISEASE-MODIFYING AGENTS

IMPLANTS AND DEVICES

JOINT REPLACEMENT
- KNEE REPLACEMENT
- HIP REPLACEMENT
- SHOULDER REPLACEMENT
- OTHER JOINT IMPLANTS
DEVICES FOR FIXATION
- WIRES
- PLATES
- NAILS OR RODS
- SCREWS
CARTILAGE TRANSPLANTATION
SYNOVIAL FLUID REPLACEMENT
ALLOGRAFTS
OTHER MATERIALS

REGULATORY ASPECTS

REGULATION OF BONE AND JOINT THERAPIES
- REGULATION IN THE U.S.
  - Devices

Table 13 FOOD AND DRUG ADMINISTRATION AGENCIES INVOLVED IN IMPLANT REGULATION
Table 14 ISO STANDARDS FOR ORTHOPAEDIC IMPLANTS
Table 14 (CONTINUED)
- DRUG APPROVALS
  - DEVICES AND IMPLANTS
Table 15 DEVICES AND IMPLANTS APPROVED BY THE FDA, 2000-2004
Table 16 LISTING OF CDRH HUMANITARIAN DEVICE EXEMPTION SUMMARIES OF SAFETY AND POSSIBLE BENEFITS, 2000-2004
Table 16 (CONTINUED)
Table 17 DRUGS APPROVED BY THE FDA, 2000-2004

INDUSTRY STRUCTURE

ORTHOPAEDIC INDUSTRY - MARKET BY COMPANY
- DRUG COMPANIES
  - NSAIDs

Table 18 MARKET SHARES OF NSAIDs IN THE ORTHOPAEDIC INDUSTRY, 2003
Figure 1 MARKET SHARES OF NSAIDs IN THE ORTHOPAEDIC INDUSTRY, 2003
Table 19 MARKET SHARES OF OPIOID ANALGESICS IN THE ORTHOPAEDIC INDUSTRY, 2003
Figure 2 MARKET SHARES OF OPIOID ANALGESICS IN THE ORTHOPAEDIC INDUSTRY, 2003
Table 20 MARKET SHARE OF CORTICOSTEROIDS IN ORTHOPAEDIC INDUSTRY IN 2003
Figure 3 MARKET SHARES OF CORTICOSTEROIDS IN THE ORTHOPAEDIC INDUSTRY, 2003
Table 21 MARKET SHARES OF BONE STABILIZERS, 2003
Figure 4 MARKET SHARES OF BONE STABILIZERS, 2003
Table 22 MARKET SHARES OF SKELETAL MUSCLE RELAXANTS USED IN ORTHOPAEDICS, 2003
Figure 5 MARKET SHARES OF SKELETAL MUSCLE RELAXANTS USED IN ORTHOPAEDICS, 2003
Table 23 MARKET SHARE OF THERAPEUTIC VITAMINS AND SUPPLEMENTS USED IN ORTHOPAEDICS, 2003
Figure 6 MARKET SHARE OF THERAPEUTIC VITAMINS AND MINERALS USED IN ORTHOPAEDICS, 2003
Table 24 MARKET SHARES OF CEPHALOSPORINS USED IN ORTHOPAEDICS, 2003
Figure 7 MARKET SHARES OF CEPHALOSPORINS USED IN ORTHOPAEDICS, 2003
Table 25 MARKET SHARES FOR MACROLIDES USED IN ORTHOPAEDICS, 2003
Figure 8 MARKET SHARES FOR MACROLIDES USED IN ORTHOPAEDICS, 2003
Table 26 MARKET SHARES FOR PENICILLINS USED IN ORTHOPAEDICS, 2003
Figure 9 MARKET SHARES FOR PENICILLINS USED IN ORTHOPAEDICS, 2003
Table 27 MARKET SHARES FOR QUINOLONES USED IN ORTHOPAEDICS, 2003
Figure 10 MARKET SHARES FOR QUINOLONES USED IN ORTHOPAEDICS, 2003
Table 28 MARKET SHARES OF TETRACYCLINES USED IN ORTHOPAEDICS, 2003
Figure 11 MARKET SHARES OF TETRACYCLINES USED IN ORTHOPAEDICS, 2003
Table 29 MARKET SHARES FOR OTHER ANTIBIOTICS USED IN ORTHOPAEDICS, 2003
Figure 12 MARKET SHARES FOR OTHER ANTIBIOTICS USED IN ORTHOPAEDICS, 2003
Table 30 MARKET SHARES FOR DISEASE-MODIFYING AGENTS USED IN ORTHOPAEDICS, 2003
Figure 13 MARKET SHARES FOR DISEASE-MODIFYING AGENTS USED IN ORTHOPAEDICS, 2003
Table 31 MARKET SHARES FOR IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2003
Figure 14 MARKET SHARES FOR IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2003

THE MARKET BY PRODUCT

ORTHOPAEDIC DRUGS

Table 32 WORLDWIDE SALES OF DRUGS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 15 WORLDWIDE SALES OF DRUGS USED IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 33 SHARES OF DRUGS USED IN ORTHOPAEDICS IN 2003
Figure 16 SHARES OF DRUGS USED IN ORTHOPAEDICS, 2003
Table 34 WORLDWIDE SALES OF NSAIDS FOR ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 17 WORLDWIDE SALES OF NSAIDS FOR ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 35 WORLDWIDE SALES OF OPIOID ANALGESICS FOR ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 18 WORLDWIDE SALES OF OPIOID ANALGESICS FOR ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 36 WORLDWIDE SALES OF CORTICOSTEROIDS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 19 WORLDWIDE SALES OF CORTICOSTEROIDS IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 37 WORLDWIDE SALES OF BONE STABILIZERS, THROUGH 2009 ($ BILLIONS)
Figure 20 WORLDWIDE SALES OF BONE STABILIZERS, 2002-2009 ($ BILLIONS)
Table 38 WORLDWIDE SALES OF SKELETAL MUSCLE RELAXANTS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 21 WORLDWIDE SALES OF SKELETAL MUSCLE RELAXANTS USED IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 39 WORLDWIDE SALES OF THERAPEUTIC VITAMINS AND MINERALS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 22 WORLDWIDE SALES OF THERAPEUTIC VITAMINS AND MINERALS USED IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 40 WORLDWIDE SALES OF ANTIBIOTICS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 23 WORLDWIDE SALES OF ANTIBIOTICS USED IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 41 WORLDWIDE SALES OF DISEASE-MODIFYING AGENTS IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 24 WORLDWIDE SALES OF DISEASE-MODIFYING AGENTS USED IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
- ORTHOPAEDIC IMPLANTS AND DEVICES
  - HIP REPLACEMENT
  - RESEARCH AND DEVELOPMENT
Table 42 IMPLANTS AND DEVICES USED IN THE ORTHOPAEDIC INDUSTRY
Table 42 (CONTINUED)
Table 42 (CONTINUED)
Table 42 (CONTINUED)
Table 42 (CONTINUED)
Table 42 (CONTINUED)
Table 42 (CONTINUED)
Table 43 WORLDWIDE SALES OF IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Figure 25 WORLDWIDE SALES OF IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2002-2009 ($ BILLIONS)
Table 44 MARKET SHARES OF IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2003
Figure 26 MARKET SHARES OF IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2003 (%)
Table 45 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE KNEE, THROUGH 2009 ($ BILLIONS)
Figure 27 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE KNEE, 2002-2009 ($ BILLIONS)
Table 46 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE HIP, THROUGH 2009 ($ BILLIONS)
Figure 28 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE HIP, 2002-2009 ($ BILLIONS)
Table 47 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE SHOULDER, THROUGH 2009 ($ BILLIONS)
Figure 29 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE SHOULDER, 2002-2009 ($ BILLIONS)
Table 48 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE SPINE, THROUGH 2009 ($ BILLIONS)
Figure 30 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE SPINE, 2002-2009 ($ BILLIONS)
Table 49 WORLDWIDE SALES OF INTERNAL AND EXTERNAL FIXATION DEVICES, THROUGH 2009 ($ BILLIONS)
Figure 31 WORLDWIDE SALES OF INTERNAL AND EXTERNAL FIXATION DEVICES, 2002-2009 ($ BILLIONS)

NEW DEVELOPMENTS

Abbott Laboratories
AstraZeneca

Table 50 NEW DRUGS BY ASTRAZENECA
Table 51 NEW DRUGS BY ELAN PHARMACEUTICALS
Table 52 NEW DRUGS BY ENDO PHARMACEUTICALS
Table 53 NEW DRUGS BY GENZYME
Table 54 NEW DRUGS BY MERCK
Table 55 NEW DRUGS BY NASTECH
Table 56 NEW DRUGS BY NOVARTIS
Table 57 NEW DRUGS BY ORTHOLOGIC
Table 58 NEW DRUGS BY ROCHE

PATENTS

PATENTS BY YEAR

Table 59 NUMBER OF PATENTS IN EACH YEAR, 2000-2004
Figure 32 NUMBER OF PATENTS IN EACH YEAR, 2000-2004
Table 60 SIGNIFICANT PATENTS FOR DRUGS USED IN ORTHOPAEDICS, 2004
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 60 (CONTINUED)
Table 61 SIGNIFICANT PATENTS FOR DRUGS USED IN ORTHOPAEDICS, 2002-2003
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 61 (CONTINUED)
Table 62 PATENTS FOR DEVICES AND IMPLANTS USED IN ORTHOPAEDICS, 2004
Table 62 (CONTINUED)
Table 62 (CONTINUED)
Table 63 SIGNIFICANT PATENTS FOR DEVICES AND IMPLANTS USED IN ORTHOPAEDICS, 2002-2003
Table 63 (CONTINUED)
- PATENTS BY COMPANY
Table 64 U.S. PATENTS BY COMPANY, 2000-2004
Figure 33 U.S. PATENTS BY COMPANY, 2000-2004
- PATENTS BY COUNTRY
Table 65 U.S. PATENTS BY COUNTRY, 2000-2004
Figure 34 U.S. PATENTS BY COUNTRY, 2000-2004
Table 66 TRENDS OF PATENTS ISSUED BY COUNTRY, 2004-2000
Figure 35 TRENDS OF PATENTS ISSUED BY COUNTRY, 2000-2004
Figure 36 TRENDS OF PATENTS ISSUED BY COUNTRY, 2000-2004
- PATENTS BY ASSIGNEE
Table 67 SHARES OF U.S. PATENTS BY ASSIGNEE, 2000-2004
Figure 37 NUMBER OF U.S. PATENTS BY ASSIGNEE, 2000-2004
Figure 38 PERCENT OF U.S. PATENTS BY ASSIGNEE, 2000-2004

INTERNATIONAL ASPECTS

Table 68 SALES OF ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, BY REGION, THROUGH 2009 ($ BILLIONS)
Figure 39 SALES OF ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, BY REGION, 2002-2009 ($ BILLIONS)
Figure 40 SHARE OF EACH REGION FOR ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, 2003 (PERCENT (%) OF TOTAL)

COMPANY PROFILES

ABBOTT LABORATORIES
ARTHROCARE
AKORN, INC.
ALCON LABORATORIES
ALLERGAN, INC.
ALEMBIC LTD.
ALPHARMA, INC.
ASTRAZENECA
AVENTIS PHARMACEUTICALS, INC.
BAXTER INTERNATIONAL, INC.
BAYER AG
BIOMET ORTHOPAEDIC, INC.
BRISTOL-MYERS SQUIBB
BIOGLAN PHARMACEUTICALS
BLACKSTONE MEDICAL, INC.
CEPHALON
CONNETICS CORP.
DERMIK LABORATORIES, INC.
DEPUY, A JOHNSON & JOHNSON COMPANY
ELAN PHARMACEUTICALS, PLC
ELI LILLY AND COMPANY
ENCORE MEDICAL CORP.
ENDO PHARMACEUTICALS
FUJISAWA HEALTHCARE, INC.
GALDERMA LABORATORIES
GENZYME BIOSURGERY
GLAXOSMITHKLINE, PLC
INNOMED, INC.
INTERPORE CROSS INTERNATIONAL
JOHNSON & JOHNSON

Table 69 THE JOHNSON & JOHNSON GROUP OF COMPANIES
Table 69 (CONTINUED)
- KING PHARMACEUTICALS
- KYPHON, INC.
- MERCK & COMPANY, INC.
- MITEK SURGICAL PRODUCTS
- MURO PHARMACEUTICALS, INC.
- NASTECH PHARMACEUTICAL CO., INC.
- NOVARTIS PHARMACEUTICAL CORP.
- OCLASSEN PHARMACEUTICALS, INC.
- ORTHOFIX, INC.
- OSTEOTECH
- PFIZER, INC.
- PROCTER & GAMBLE
- PURDUE PHARMA
- ROCHE
- ROXANE LABORATORIES, INC.
- RUSH/BERIVON, INC.
- SANOFI-SYNTHELABO
- SANTEN, INC.
- SCHERING-PLOUGH
- SMITH & NEPHEW ORTHOPAEDICS
  - SMITH & NEPHEW ORTHOPAEDICS (CONTINUED)
- STRYKER ORTHOPAEDICS
- VALEANT PHARMACEUTICALS
- WYETH PHARMACEUTICALS
- WRIGHT MEDICAL TECHNOLOGY
- ZIMMER HOLDINGS, INC.

LIST OF TABLES

Summary Table: GLOBAL SALES OF ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, THROUGH 2009 ($ BILLIONS)
Table 1 COMMON ORTHOPAEDIC DISORDERS
Table 2 TYPES OF TREATMENTS FOR FRACTURES
Table 3 NON-OPIOID DRUGS USED AS ANALGESICS, ANTI-INFLAMMATORIES, AND ANTIPYRETICS
Table 4 OPIOID DRUGS USED AS ANALGESICS
Table 5 CLASSIFICATION OF CORTICOSTEROIDS
Table 6 CORTICOSTERIOD DRUGS USED AS ANTI-INFLAMMATORYS
Table 7 DRUGS USED AS BONE STABILIZERS
Table 8 DRUGS USED AS SKELETAL MUSCLE RELAXANTS
Table 9 DRUGS USED AS VITAMIN SUPPLEMENTS
Table 10 DRUGS USED AS CALCIUM SUPPLEMENTS
Table 11 DRUGS USED AS ANTIBIOTICS
Table 12 DISEASE-MODIFYING AGENTS
Table 13 FOOD AND DRUG ADMINISTRATION AGENCIES INVOLVED IN IMPLANT REGULATION
Table 14 ISO STANDARDS FOR ORTHOPAEDIC IMPLANTS
Table 15 DEVICES AND IMPLANTS APPROVED BY THE FDA, 2000-2004
Table 16 LISTING OF CDRH HUMANITARIAN DEVICE EXEMPTION SUMMARIES OF SAFETY AND POSSIBLE BENEFITS, 2000-2004
Table 17 DRUGS APPROVED BY THE FDA, 2000-2004
Table 18 MARKET SHARES OF NSAIDs IN THE ORTHOPAEDIC INDUSTRY, 2003
Table 19 MARKET SHARES OF OPIOID ANALGESICS IN THE ORTHOPAEDIC INDUSTRY, 2003
Table 20 MARKET SHARE OF CORTICOSTEROIDS IN ORTHOPAEDIC INDUSTRY IN 2003
Table 21 MARKET SHARES OF BONE STABILIZERS, 2003
Table 22 MARKET SHARES OF SKELETAL MUSCLE RELAXANTS USED IN ORTHOPAEDICS, 2003
Table 23 MARKET SHARE OF THERAPEUTIC VITAMINS AND SUPPLEMENTS USED IN ORTHOPAEDICS, 2003
Table 24 MARKET SHARES OF CEPHALOSPORINS USED IN ORTHOPAEDICS, 2003
Table 25 MARKET SHARES FOR MACROLIDES USED IN ORTHOPAEDICS, 2003
Table 26 MARKET SHARES FOR PENICILLINS USED IN ORTHOPAEDICS, 2003
Table 27 MARKET SHARES FOR QUINOLONES USED IN ORTHOPAEDICS, 2003
Table 28 MARKET SHARES OF TETRACYCLINES USED IN ORTHOPAEDICS, 2003
Table 29 MARKET SHARES FOR OTHER ANTIBIOTICS USED IN ORTHOPAEDICS, 2003
Table 30 MARKET SHARES FOR DISEASE-MODIFYING AGENTS USED IN ORTHOPAEDICS, 2003
Table 31 MARKET SHARES FOR IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2003
Table 32 WORLDWIDE SALES OF DRUGS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 33 SHARES OF DRUGS USED IN ORTHOPAEDICS IN 2003
Table 34 WORLDWIDE SALES OF NSAIDS FOR ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 35 WORLDWIDE SALES OF OPIOID ANALGESICS FOR ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 36 WORLDWIDE SALES OF CORTICOSTEROIDS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 37 WORLDWIDE SALES OF BONE STABILIZERS, THROUGH 2009 ($ BILLIONS)
Table 38 WORLDWIDE SALES OF SKELETAL MUSCLE RELAXANTS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 39 WORLDWIDE SALES OF THERAPEUTIC VITAMINS AND MINERALS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 40 WORLDWIDE SALES OF ANTIBIOTICS USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 41 WORLDWIDE SALES OF DISEASE-MODIFYING AGENTS IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 42 IMPLANTS AND DEVICES USED IN THE ORTHOPAEDIC INDUSTRY
Table 43 WORLDWIDE SALES OF IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, THROUGH 2009 ($ BILLIONS)
Table 44 MARKET SHARES OF IMPLANTS AND DEVICES USED IN ORTHOPAEDICS, 2003
Table 45 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE KNEE, THROUGH 2009 ($ BILLIONS)
Table 46 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE HIP, THROUGH 2009 ($ BILLIONS)
Table 47 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE SHOULDER, THROUGH 2009 ($ BILLIONS)
Table 48 WORLDWIDE SALES OF THERAPEUTIC PRODUCTS TO REPAIR THE SPINE, THROUGH 2009 ($ BILLIONS)
Table 49 WORLDWIDE SALES OF INTERNAL AND EXTERNAL FIXATION DEVICES, THROUGH 2009 ($ BILLIONS)
Table 50 NEW DRUGS BY ASTRAZENECA
Table 51 NEW DRUGS BY ELAN PHARMACEUTICALS
Table 52 NEW DRUGS BY ENDO PHARMACEUTICALS
Table 53 NEW DRUGS BY GENZYME
Table 54 NEW DRUGS BY MERCK
Table 55 NEW DRUGS BY NASTECH
Table 56 NEW DRUGS BY NOVARTIS
Table 57 NEW DRUGS BY ORTHOLOGIC
Table 58 NEW DRUGS BY ROCHE
Table 59 NUMBER OF PATENTS IN EACH YEAR, 2000-2004
Table 60 SIGNIFICANT PATENTS FOR DRUGS USED IN ORTHOPAEDICS, 2004
Table 61 SIGNIFICANT PATENTS FOR DRUGS USED IN ORTHOPAEDICS, 2002-2003
Table 62 PATENTS FOR DEVICES AND IMPLANTS USED IN ORTHOPAEDICS, 2004
Table 63 SIGNIFICANT PATENTS FOR DEVICES AND IMPLANTS USED IN ORTHOPAEDICS, 2002-2003
Table 64 U.S. PATENTS BY COMPANY, 2000-2004
Table 65 U.S. PATENTS BY COUNTRY, 2000-2004
Table 66 TRENDS OF PATENTS ISSUED BY COUNTRY, 2004-2000
Table 67 SHARES OF U.S. PATENTS BY ASSIGNEE, 2000-2004
Table 68 SALES OF ORTHOPAEDIC DRUGS, IMPLANTS, AND DEVICES, BY REGION, THROUGH 2009 ($ BILLIONS)
Table 69 THE JOHNSON & JOHNSON GROUP OF COMPANIES

Orthopedic Drugs, Implants and Devices

Publisher: Business Communications Co., Inc.

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Orthopedic Drugs, Implants and Devices

SUMMARY

REPORT HIGHLIGHTS

INTRODUCTION

SCOPE OF STUDY

METHODOLOGY

INFORMATION SOURCES

TABLE OF CONTENTS

LIST OF TABLES