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Membrane Technology for Biopharmaceuticals
Product Type: Market Research Report Publication Date: Nov 08, 2004
 
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SUMMARY

To facilitate the identification of tiny molecular variations, or mutations, life science companies developed increasingly advanced and very-high-throughput automated analytical systems. Membranes are an enabling technology in all phases of the process used to bring biotech drugs to market, from laboratory research to large-scale pharmaceutical manufacturing.

Membranes ease the handling of biological samples for microscopic analysis and are used in the laboratory setting for the transfer, immobilization and detection of DNA, RNA and proteins. Other lab-scale applications include sterilization of cell culture media, particulate removal and solution clarification. The generation of ultrapure water, essential to the life science lab, also is made possible by point of use membrane filtration systems.

Large-scale bioprocessing applications for membranes are found in the production of vitamins, vaccines, antibiotics, therapeutic protein drugs and monoclonal antibodies, where filtration systems are used for purification and clarification of various biological solutions. Cells grown in membrane bioreactors secrete valuable products for therapeutic drug manufacture. The removal of potentially harmful viruses encountered in drug production also may be accomplished using membranes.

This BCC technical market report provides an in-depth analysis of the market for membrane technology across a range of life science/biotech applications including gene and protein analysis, drug candidate screening, laboratory separations and water treatment, cell culture, virus removal and drug production, all of which are vital to the pharmaceutical industrys continued success.

SCOPE OF STUDY

The report contains:

  • An overview and history of the industry
  • In-depth analysis of the markets for membrane technology vital to bringing drug products to market including:
      - gene and protein analysis
      - drug candidate screening
      - laboratory separations and water treatment
      - cell culture
      - virus removal
      - drug production
  • Five-year projections through 2009 for market activity and value
  • Industry structure, technological trends, pricing considerations, R&D, government regulations, company profiles and competitive technologies.

TABLE OF CONTENTS

  • INTRODUCTION
      • STUDY GOALS AND OBJECTIVES
      • REASONS FOR DOING STUDY
      • CONTRIBUTION OF THE STUDY AND FOR WHOM
      • SCOPE AND FORMAT
      • METHODOLOGY
      • INFORMATION SOURCES
      • AUTHOR'S CREDENTIALS
      • RELATED BCC WORK CREDENTIALS
      • BCC ON-LINE SERVICES
      • DISCLAIMER
  • SUMMARY
    • Summary Table: U.S. MARKET VALUE OF MEMBRANE TECHNOLOGY FOR THE LIFE SCIENCE INDUSTRY, THROUGH 2009 ($ MILLIONS)
    • Summary Figure: U.S. MARKET VALUE OF MEMBRANE TECHNOLOGY FOR THE LIFE SCIENCE INDUSTRY, 2002-2009
  • INDUSTRY OVERVIEW
      • HISTORY OF THE INDUSTRY
    • Table 1 A BRIEF HISTORY OF MEMBRANES IN THE LIFE SCIENCES
    • Table 1 (CONTINUED)
      • BIOPHARMACEUTICALS
        • DRUG DISCOVERY, DEVELOPMENT AND MANUFACTURING
          • Drug Discovery, Development(Continued)
    • Figure 1 NEW DRUGS: FROM DISCOVERY TO MANUFACTURING
          • Approval Process Improving
          • Harmonization
        • DRUG DEVELOPMENT COSTS
          • Research Funding
            • Government Funding
            • Venture Capital Funding
            • Corporate Funding
        • COMMERCIAL BIOTECH DRUGS
    • Table 2 NEW DRUG APPROVALS IN RELATION TO R&D SPENDING, 1999-2003 (NUMBER, $ BILLIONS)
    • Figure 2 NEW DRUG APPROVALS IN RELATION TO R&D SPENDING, 1992-2003 (NUMBER, $ BILLIONS)
    • Table 3 TOP TEN BIOTECH DRUGS, GLOBAL MARKET, 2003 ($ MILLIONS)
        • ORPHAN DRUGS
        • BIOGENERICS
    • Table 4 LEADING BIOPHARMACEUTICALS FACING GENERIC STATUS
      • MEMBRANE TECHNOLOGY
        • MEMBRANE MATERIALS
    • Table 5 CHARACTERISTICS OF MEMBRANE MATERIALS
        • MODULES
        • CONFIGURATION
        • MOLECULAR WEIGHT CUTOFF
        • FLUX
          • Fouling
      • METHODS OF FILTRATION
        • DIRECT FLOW FILTRATION
        • CROSSFLOW FILTRATION
      • MEMBRANE TECHNOLOGY TYPES
        • REVERSE OSMOSIS
        • NANOFILTRATION
        • ULTRAFILTRATION
        • MICROFILTRATION
          • MF vs. UF in Bioseparations
    • Table 6 BIOPHARMACEUTICAL APPLICATIONS OF UF AND MF
        • ELECTRODEIONIZATION
      • COMPETITIVE TECHNOLOGIES
    • Table 7 VALUE OF THE U.S. MARKET FOR MEMBRANE FILTRATION AND COMPETITIVE BIOSEPARATION METHODS, THROUGH 2009 ($ MILLIONS )
    • Figure 3 VALUE OF THE U.S. MARKET FOR MEMBRANE FILTRATION AND COMPETITIVE BIOSEPARATION METHODS, 2002-2009 ($ MILLIONS)
  • LIFE SCIENCE APPLICATIONS FOR MEMBRANE TECHNOLOGY
      • LIFE SCIENCE APPLICATIONS FOR MEMBRANE TECHNOLOGY
        • LIFE SCIENCE APPLICATIONS FOR (CONTINUED)
    • Table 8 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES BY LIFE SCIENCE APPLICATIONS, THROUGH 2009 ($ MILLIONS)
    • Figure 4 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES BY LIFE SCIENCE APPLICATIONS, 2002-2009 ($ MILLIONS)
  • LABORATORY-SCALE APPLICATIONS
      • GENOMICS RESEARCH
        • TRANSFER MEMBRANES
          • Types of Blots
            • Southern Blot
            • Western Blot
            • Colony or Plaque Blot
          • Transfer Membrane Manufacturers/Products
    • Table 9 TRANSFER MEMBRANE MANUFACTURERS/PRODUCTS
        • DNA MICROARRAYS
          • DNA Microarray Membranes
          • DNA Array Manufacturers/Products
    • Table 10 DNA MICROARRAY MANUFACTURERS/PRODUCTS
      • PROTEOMICS RESEARCH
        • PROTEIN ARRAYS
          • Protein Array Membranes
          • Protein Array Manufacturers/Products
    • Table 11 PROTEIN ARRAY MANUFACTURERS/ PRODUCTS
      • CANDIDATE DRUG SCREENING
        • MULTI-WELL FILTER PLATES
          • ADMET Screening
          • Solubility Assays
          • PAMPA-Parallel Artificial Membrane Permeation Assays
          • Caco-2 and Other Cell-Based Transport Assays
          • Bound vs. Free Drug Assays
          • Total Drug Analysis
          • DNA Sample Preparation
          • Multiwell Filter Plate Manufacturers/Products
    • Table 12 MULTIWELL FILTER PLATE MANUFACTURERS/PRODUCTS
    • Table 12 (CONTINUED)
    • Table 12 (CONTINUED)
    • Table 12 (CONTINUED)
      • LAB-SCALE SEPARATIONS
        • SYRINGE FILTERS
          • Syringeless Filters
          • Syringe/ Syringeless Filter Manufacturers/ Products
    • Table 13 SYRINGE AND SYRINGELESS FILTER MANUFACTURERS
    • Table 13 (CONTINUED)
    • Table 13 (CONTINUED)
    • Table 13 (CONTINUED)
        • BOTTLE-TOP FILTERS
          • Bottletop Filter Manufacturers/ Products
    • Table 14 BOTTLETOP FILTER MANUFACTURERS/PRODUCTS
    • Table 14 (CONTINUED)
        • MOLECULAR SEPARATIONS SYSTEMS
          • Stirred Cell Systems
            • Stirred Cell Manufacturers/ Products
    • Table 15 STIRRED CELL MANUFACTURERS/PRODUCTS
          • Centrifugal Devices
            • Centrifuge Filter Manufacturers/ Products
    • Table 16 CENTRIFUGAL FILTER MANUFACTURERS
    • Table 16 (CONTINUED)
          • TFF Systems
            • TFF Replacing Centrifugal, Stirred Cell Systems
            • TFF System Manufacturers/Products
    • Table 17 LAB-SCALE, PILOT-SCALE, SMALL PRODUCTION-SCALE TFF SYSTEMS
    • Table 17 (CONTINUED)
    • Table 17 (CONTINUED)
      • LABORATORY WATER
        • VALIDATING LAB WATER SYSTEMS
          • Lab Water System Manufacturers/Products
    • Table 18 LABORATORY WATER SYSTEM MANUFACTURERS/PRODUCTS
    • Table 18 (CONTINUED)
      • VALUE OF THE U.S. MARKET FOR LAB-SCALE DEVICES/SYSTEMS
        • TRANSFER MEMBRANES
        • MICROARRAYS
        • MULTIWELL PLATES
        • SYRINGE FILTERS, BOTTLETOP FILTERS
        • MOLECULAR SEPARATION SYSTEMS
        • LABORATORY WATER SYSTEMS
    • Table 19 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES IN LAB-SCALE APPLICATIONS BY DEVICE/SYSTEM TYPE, THROUGH 2009 ($ MILLIONS)
    • Figure 5 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES IN LAB-SCALE APPLICATIONS BY DEVICE/SYSTEM TYPE, 2002-2009 ($ MILLIONS)
  • CELL CULTURING APPLICATIONS
      • OVERVIEW
      • CELL CULTURE SYSTEMS
        • CELL CULTURE INSERTS
          • Membrane Insert Manufacturers/Products
            • Becton Dickinson
            • Millipore
            • Corning
        • CELL CULTURE REACTORS
          • Cell Culture Reactor Manufacturers/Products
    • Table 20 CELL CULTURE REACTOR MANUFACTURERS/PRODUCTS
    • Table 20 (CONTINUED)
      • VALUE OF THE U.S. MARKET FOR CELL CULTURE SYSTEMS
        • VALUE OF THE U.S. MARKET FOR(CONTINUED)
    • Table 21 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES IN CELL CULTURE SYSTEMS, THROUGH 2009 ($ MILLIONS)
    • Figure 6 VALUE OF THE U.S. MARKET FOR CELL CULTURE SYSTEMS, 2002-2009 ($ MILLIONS)
  • PROCESS-SCALE APPLICATIONS
    • Table 22 PROCESS-SCALE BIOTECH PURIFICATIONS
      • CONVENTIONAL MANUFACTURING
        • REVAMPED REGULATIONS
      • PROTEIN SEPARATIONS/CONCENTRATION
    • Figure 7 BIOPHARMACEUTICALS MANUFACTURE
    • Figure 8 VACCINE MANUFACTURE
    • Figure 9 ANTIBIOTIC AND VITAMIN MANUFACTURE
        • BIOPROCESSING MEMBRANES AND SYSTEMS
          • Bioprocessing Equipment Manufacturers/Products
    • Table 23 UF, MF MEMBRANE/SYSTEM MANUFACTURERS AND PRODUCTS
    • Table 23 (CONTINUED)
    • Table 23 (CONTINUED)
      • VIRUS REMOVAL
        • VIRUS FILTERS
    • Table 24 VIRUSES FOUND IN BIOPHARMACEUTICAL PRODUCTION
          • Virus Filter Manufacturers/Products
    • Table 25 VIRUS FILTER MANUFACTURERS/PRODUCTS
      • MEMBRANE CHROMATOGRAPHY
        • MEMBRANE ADSORBERS
          • Membrane Adsorber Manufacturers/Products
    • Table 26 MEMBRANE ADSORBER MANUFACTURERS/PRODUCTS
    • Table 26 (CONTINUED)
      • CHIRAL SEPARATIONS
      • COMPENDIAL WATERS
        • PROCESS WATER MEMBRANE AND SYSTEMS
          • Manufacturers of Process Water Treatment Membranes/Systems
    • Table 27 PROCESS WATER EQUIPMENT MANUFACTURERS/PRODUCTS
      • VALUE OF THE U.S. MARKET FOR PROCESS-SCALE DEVICES/SYSTEMS
    • Table 28 MANUFACTURERS USING MEMBRANES IN APPROVED BIOTECH DRUG PRODUCTION
        • THE BIOMANUFACTURING CRUNCH
        • MF BIOPROCESSING
        • UF BIOPROCESSING
        • VIRUS REDUCTION
        • MEMBRANE CHROMATOGRAPHY
        • PROCESS WATER TREATMENT
    • Table 29 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES BY PROCESS-SCALE DEVICE/SYSTEM TYPE, THROUGH 2009 ($ MILLIONS)
    • Figure 10 VALUE OF THE U.S. MARKET BY PROCESS-SCALE DEVICE/SYSTEM TYPE, 2002-2009 ($ MILLIONS)
  • PATENTS, TRENDS AND TECHNICAL DEVELOPMENTS
      • PATENT SURVEY
        • PATENTS BY APPLICATION
    • Table 30 PATENT SURVEY BY APPLICATION (APRIL 1, 1999-MARCH 31, 2004)
    • Table 30 (CONTINUED)
    • Figure 11 PATENT SURVEY BY APPLICATION (APRIL 1, 1999-MARCH 31, 2004)
        • BY COMPANY
    • Table 31 PATENT SURVEY BY COMPANY (APRIL 1, 1999-MARCH 31, 2004)
    • Figure 12 PATENT SURVEY BY COMPANY (APRIL 1, 1999-MARCH 31, 2004)
      • TRENDS
        • DISPOSABLE MANUFACTURING
          • Disposable Manufacturing (Continued)
      • TECHNICAL DEVELOPMENTS
        • POLYMER BRUSH ADSORBERS
        • ANTIBODY-BASED NANOTUBE MEMBRANES
        • LIPID MEMBRANE CELL CULTURE MICROARRAYS
        • P-FILM
        • GRADIFLOW
  • INTERNATIONAL ASPECTS
    • Table 32 GLOBAL BIOTECH AND PHARMA R&D SPENDING, 1995-2003 ($ BILLIONS)
    • Figure 13 GLOBAL BIOTECH AND PHARMA R&D SPENDING, 1995-2003 ($ BILLIONS)
    • Table 33 GLOBAL BIOTECH AND PHARMA R&D SPENDING BY COUNTRY, 2003 ($ MILLIONS)
    • Figure 14 GLOBAL BIOTECH AND PHARMA R&D SPENDING BY COUNTRY, 2003 ($ MILLIONS)
      • WESTERN EUROPE
    • Table 34 BIOTECH COMPANIES AND PRODUCT PIPELINES IN EUROPE, 2002
    • Figure 15 BIOTECH COMPANIES AND PRODUCT PIPELINES IN EUROPE, 2002
        • UK
        • FRANCE
        • GERMANY
        • ITALY
        • THE NETHERLANDS
        • SPAIN
        • BELGIUM
        • SWEDEN
        • DENMARK
        • NORWAY
        • FINLAND
        • ICELAND
      • EASTERN EUROPE
        • ESTONIA
        • CROATIA
        • LITHUANIA
        • RUSSIA
      • MIDDLE EAST
        • ISRAEL
      • ASIA
        • CHINA
        • JAPAN
        • INDIA
        • TAIWAN
        • SINGAPORE
        • SOUTH KOREA
      • REST OF WORLD
        • AUSTRALIA
        • BRAZIL
      • GLOBAL LIFE SCIENCE MEMBRANE MARKET
        • GLOBAL LIFE SCIENCE MEMBRANE (CONTINUED)
  • INDUSTRY STRUCTURE
    • Table 35 LIFE SCIENCE EQUIPMENT CUSTOMERS (%)
    • Figure 16 LIFE SCIENCE EQUIPMENT CUSTOMERS (%)
      • BIOTECH AND BIG PHARMA
        • BLURRING BOUNDARIES
        • MANUFACTURERS OF MEMBRANES, DEVICES AND SYSTEMS SUPPORTING THE LIFE SCIENCE INDUSTRY
          • Manufacturers of Membranes, Devices (Continued)
          • Consolidation
          • The Urge to Merge
    • Table 36 MEMBRANE INDUSTRY MERGERS AND ACQUISITIONS RELATED TO THE LIFE SCIENCES (1994-JULY 2004)
        • PARTNERING AGREEMENTS
    • Table 37 SELECTED PARTNERING AGREEMENTS (2000-JULY 2004)
    • Table 37 (CONTINUED)
      • MARKET SHARE
    • Table 38 ESTIMATED COMPANY MARKET SHARES IN THE LIFE SCIENCE MEMBRANE INDUSTRY, 2004 (%)
    • Figure 17 ESTIMATED COMPANY MARKET SHARES IN THE LIFE SCIENCE MEMBRANE INDUSTRY, 2004 (%)
    • Table 39 MAJOR MANUFACTURERS AND PRODUCT TYPES
        • ECOMMERCE
      • COMPANY PROFILES
        • 20/20 GENESYSTEMS
        • ADVANTEC MFS, INC.
        • AMBION
        • AMERSHAM BIOSCIENCES/GE
        • ASAHI KASEI
        • BECTON DICKINSON
          • Discovery Labware
          • BD Clontech
        • BIOVEST INTERNATIONAL
        • CORNING, INC.
        • CUNO, INC.
        • ELGA LABWATER
        • EMEMBRANE
        • FIBERCELL SYSTEMS, INC.
        • GE OSMONICS
        • HYDRANAUTICS
        • IONICS, INC.
        • INTEGRA BIOSCIENCES
        • KOCH MEMBRANE SYSTEMS
        • MEISSNER FILTRATION PRODUCTS, INC.
        • MILLIPORE
        • PALL
        • PCI MEMBRANES
        • SCHLEICHER & SCHUELL
        • SARTORIUS AG
        • SPECTRUM LABORATORIES
        • STERLITECH
        • SYNDER FILTRATION
        • SYNTHECON
        • TAMI INDUSTRIES
        • TORAY INDUSTRIES
        • TRISEP
        • USFILTER/SIEMENS AG
        • WHATMAN PLC
  • APPENDIX
      • CONTACTS
    • Table 40 MANUFACTURERS DIRECTORY
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
    • Table 40 (CONTINUED)
      • PATENTS
    • Table 41 PATENT SURVEY
    • Table 41 (CONTINUED)
    • Table 41 (CONTINUED)
    • Table 41 (CONTINUED)
    • Table 41 (CONTINUED)
    • Table 41 (CONTINUED)
      • BIOTECH DRUGS IN U.S. PIPELINE
    • Table 42 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-HIV/AIDS
    • Table 43 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-AUTOIMMUNE DISORDERS
    • Table 43 (CONTINUED)
    • Table 44 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-BLOOD DISORDERS
    • Table 45 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-CANCER AND RELATED CONDITIONS
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 45 (CONTINUED)
    • Table 46 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-DIABETES AND RELATED CONDITIONS
    • Table 47 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-DIGESTIVE DISORDERS
    • Table 47 (CONTINUED)
    • Table 48 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-EYE CONDITIONS
    • Table 49 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-GENETIC DISORDERS
    • Table 50 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-GROWTH DISORDERS
    • Table 50 (CONTINUED)
    • Table 51 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-HEART DISEASE
    • Table 51 (CONTINUED)
    • Table 52 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-INFECTIOUS DISEASES
    • Table 52 (CONTINUED)
    • Table 52 (CONTINUED)
    • Table 52 (CONTINUED)
    • Table 53 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-INFERTILITY
    • Table 54 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-NEUROLOGIC DISORDERS
    • Table 54 (CONTINUED)
    • Table 55 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-RESPIRATORY DISORDERS
    • Table 55 (CONTINUED)
    • Table 55 (CONTINUED)
    • Table 56 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-SKIN DISORDERS
    • Table 56 (CONTINUED)
    • Table 57 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-TRANSPLANTATION
    • Table 57 (CONTINUED)
    • Table 58 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-OTHER
    • Table 58 (CONTINUED)
    • Table 58 (CONTINUED)
      • APPROVED BIOTECH DRUGS
    • Table 59 APPROVED BIOTECH DRUGS (AS OF FEBRUARY 2004)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
    • Table 59 (CONTINUED)
  • Summary Table:
  • Table 1 A BRIEF HISTORY OF MEMBRANES IN THE LIFE SCIENCES
  • Table 2 NEW DRUG APPROVALS IN RELATION TO R&D SPENDING, 1992-2003 (NUMBER, $ BILLIONS)
  • Table 3 TOP TEN BIOTECH DRUGS, GLOBAL MARKET, 2003 ($ MILLIONS)
  • Table 4 LEADING BIOPHARMACEUTICALS FACING GENERIC STATUS
  • Table 5 CHARACTERISTICS OF MEMBRANE MATERIALS
  • Table 6 BIOPHARMACEUTICAL APPLICATIONS OF UF AND MF
  • Table 7 VALUE OF THE U.S. MARKET FOR MEMBRANE FILTRATION AND COMPETITIVE BIOSEPARATION METHODS, THROUGH 2009 ($ MILLIONS )
  • Table 8 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES BY LIFE SCIENCE APPLICATIONS, THROUGH 2009 ($ MILLIONS)
  • Table 9 TRANSFER MEMBRANE MANUFACTURERS/PRODUCTS
  • Table 10 DNA MICROARRAY MANUFACTURERS/PRODUCTS
  • Table 11 PROTEIN ARRAY MANUFACTURERS/PRODUCTS
  • Table 12 MULTIWELL FILTER PLATE MANUFACTURERS/PRODUCTS
  • Table 13 SYRINGE AND SYRINGELESS FILTER MANUFACTURERS
  • Table 14 BOTTLETOP FILTER MANUFACTURERS/PRODUCTS
  • Table 15 STIRRED CELL MANUFACTURERS/PRODUCTS
  • Table 16 CENTRIFUGAL FILTER MANUFACTURERS
  • Table 17 LAB-SCALE, PILOT-SCALE, SMALL PRODUCTION-SCALE TFF SYSTEMS
  • Table 18 LABORATORY WATER SYSTEM MANUFACTURERS/PRODUCTS
  • Table 19 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES IN LAB-SCALE APPLICATIONS BY DEVICE/SYSTEM TYPE, THROUGH 2009 ($ MILLIONS)
  • Table 20 CELL CULTURE REACTOR MANUFACTURERS/PRODUCTS
  • Table 21 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES IN CELL CULTURE SYSTEMS, THROUGH 2009 ($ MILLIONS)
  • Table 22 PROCESS-SCALE BIOTECH PURIFICATIONS
  • Table 23 UF, MF MEMBRANE/SYSTEM MANUFACTURERS AND PRODUCTS
  • Table 24 VIRUSES FOUND IN BIOPHARMACEUTICAL PRODUCTION
  • Table 25 VIRUS FILTER MANUFACTURERS/PRODUCTS
  • Table 26 MEMBRANE ADSORBER MANUFACTURERS/PRODUCTS
  • Table 27 PROCESS WATER EQUIPMENT MANUFACTURERS/PRODUCTS
  • Table 28 MANUFACTURERS USING MEMBRANES IN APPROVED BIOTECH DRUG PRODUCTION
  • Table 29 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES BY PROCESS-SCALE DEVICE/SYSTEM TYPE, THROUGH 2009 ($ MILLIONS)
  • Table 30 PATENT SURVEY BY APPLICATION (APRIL 1, 1999-MARCH 31, 2004)
  • Table 31 PATENT SURVEY BY COMPANY (APRIL 1, 1999-MARCH 31, 2004)
  • Table 32 GLOBAL BIOTECH AND PHARMA R&D SPENDING, 1995-2003 ($ BILLIONS)
  • Table 33 GLOBAL BIOTECH AND PHARMA R&D SPENDING BY COUNTRY, 2003 ($ MILLIONS)
  • Table 34 BIOTECH COMPANIES AND PRODUCT PIPELINES IN EUROPE, 2002
  • Table 35 LIFE SCIENCE EQUIPMENT CUSTOMERS (%)
  • Table 36 MEMBRANE INDUSTRY MERGERS AND ACQUISITIONS RELATED TO THE LIFE SCIENCES (1994-JULY 2004)
  • Table 37 SELECTED PARTNERING AGREEMENTS (2000-JULY 2004)
  • Table 38 ESTIMATED COMPANY MARKET SHARES IN THE LIFE SCIENCE MEMBRANE INDUSTRY, 2004 (%)
  • Table 39 MAJOR MANUFACTURERS AND PRODUCT TYPES
  • Table 40 MANUFACTURERS DIRECTORY
  • Table 41 PATENT SURVEY
  • Table 42 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-HIV/AIDS
  • Table 43 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-AUTOIMMUNE DISORDERS
  • Table 44 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-BLOOD DISORDERS
  • Table 45 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-CANCER AND RELATED CONDITIONS
  • Table 46 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-DIABETES AND RELATED CONDITIONS
  • Table 47 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-DIGESTIVE DISORDERS
  • Table 48 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-EYE CONDITIONS
  • Table 49 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-GENETIC DISORDERS
  • Table 50 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-GROWTH DISORDERS
  • Table 51 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-HEART DISEASE
  • Table 52 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-INFECTIOUS DISEASES
  • Table 53 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-INFERTILITY
  • Table 54 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-NEUROLOGIC DISORDERS
  • Table 55 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-RESPIRATORY DISORDERS
  • Table 56 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-SKIN DISORDERS
  • Table 57 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-TRANSPLANTATION
  • Table 58 BIOTECHNOLOGY MEDICINES IN DEVELOPMENT-OTHER
  • Table 59 APPROVED BIOTECH DRUGS (AS OF FEBRUARY 2004)
  • Summary Figure:
  • Figure 1 NEW DRUGS: FROM DISCOVERY TO MANUFACTURING
  • Figure 2 NEW DRUG APPROVALS IN RELATION TO R&D SPENDING, 1992-2003 (NUMBER, $ BILLIONS)
  • Figure 3 VALUE OF THE U.S. MARKET FOR MEMBRANE FILTRATION AND COMPETITIVE BIOSEPARATION METHODS, 2002-2009 ($ MILLIONS)
  • Figure 4 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES BY LIFE SCIENCE APPLICATIONS, 2002-2009 ($ MILLIONS)
  • Figure 5 VALUE OF THE U.S. MARKET FOR MEMBRANE TECHNOLOGIES IN LAB-SCALE APPLICATIONS BY DEVICE/SYSTEM TYPE, 2002-2009 ($ MILLIONS)
  • Figure 6 VALUE OF THE U.S. MARKET FOR CELL CULTURE SYSTEMS, 2002-2009 ($ MILLIONS)
  • Figure 7 BIOPHARMACEUTICALS MANUFACTURE
  • Figure 8 VACCINE MANUFACTURE
  • Figure 9 ANTIBIOTIC AND VITAMIN MANUFACTURE
  • Figure 10 VALUE OF THE U.S. MARKET BY PROCESS-SCALE DEVICE/SYSTEM TYPE, 2002-2009 ($ MILLIONS)
  • Figure 11 PATENT SURVEY BY APPLICATION (APRIL 1, 1999-MARCH 31, 2004)
  • Figure 12 PATENT SURVEY BY COMPANY (APRIL 1, 1999-MARCH 31, 2004)
  • Figure 13 GLOBAL BIOTECH AND PHARMA R&D SPENDING, 1995-2003 ($ BILLIONS)
  • Figure 14 GLOBAL BIOTECH AND PHARMA R&D SPENDING BY COUNTRY, 2003 ($ MILLIONS)
  • Figure 15 BIOTECH COMPANIES AND PRODUCT PIPELINES IN EUROPE, 2002
  • Figure 16 LIFE SCIENCE EQUIPMENT CUSTOMERS (%)
  • Figure 17 ESTIMATED COMPANY MARKET SHARES IN THE LIFE SCIENCE MEMBRANE INDUSTRY, 2004 (%)

Membrane Technology for Biopharmaceuticals

Publisher: Business Communications Co., Inc.

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