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SUMMARY
Orthopedic biomaterial products, which can be organic or synthetic in nature,
are implanted into or near a bone fracture to facilitate healing or to
compensate for a lack or loss of bone tissue. Biomaterials used in orthopedic
surgery include autografts, allografts, xenografts, ceramics, polymers, bone
growth factors and synovial fluid substitutes. Among the prominent
applications for orthopedic biomaterials are surface coatings for hip
prostheses, bone cements, bone defect fillers, and fracture fixation plates.
Technological advancement and an aging, active population are the principal
drivers behind the market for orthopedic biomaterials. Kalorama's Orthopedic
Biomaterials, World Market, one of the few resources available on this market,
looks at the Market for biomaterials, including the following segments:
- Allograft Products (including DBM, Machined Bone and Standard Allograft)
- Ceramic Products
- Polymer Products
- rhBMP Products
- HA Viscosupplemental Products
As part of Kalorama Information's exhaustive coverage of the orthopedic
biomaterials market for each area, the following data are provided:
- Historical Revenues from 2001-2005
- Forecasts to 2012
- Competitive Market Share
- Discussion of Issues and Trends
- Review of New Products
- Company Profiles
A truly global resource, this report provides information on the following
world regions:
- US
- Europe
- Asia
- Rest of World
The information for this report was gathered using both primary and secondary
research including comprehensive research of secondary sources such as company
literature, databases, investment reports, and medical and business journals.
Telephone interviews and email correspondence were the primary method of
gathering information.
For the purpose of this study, Kalorama Information conducted interviews with
key industry officials, consultants, health care providers, orthopedic
surgeons, research institutes, and government personnel. These sources were
the primary basis for information specifically relating to trends in the
orthopedic biomaterials industry, revenue and market share data presented in
this report. Specific interviews with orthopedic implant device and
biomaterial company representatives included marketing directors, division
managers, and product representatives.
TABLE OF CONTENTS
CHAPTER ONE: EXECUTIVE SUMMARY
- Overview
- Scope and Methodology
- Musculoskeletal Conditions/Treatments
- Prevelance of Musculoskeletal Conditions
- Most Common Musculoskeletal Conditions
- Joint Replacement Procedures
- Future Directions in the Treatment of Musculoskeletal Conditions
- Gene Therapy
- Stem Cell Therapy
- Orthopedic Biomaterials Products and Markets
- World Orthopedic Biomaterials Market
- Market Segment Analysis
- Allograft Bone Substitutes
- Ceramic Bone Substitutes
- Polymer Bone Substitutes
- rhBMP
- HA Viscosupplemental Substitutes
CHAPTER TWO: INTRODUCTION
- Overview of the Form/Function of Bone
- Bone Characteristics
- Types of Bone
- Cortical Bone
- Cancellous Bone
- Bone Cells
- Osteoblasts
- Osteoclasts
- Osteocytes
- The Functions of Bone
- Bone Matrix
- Joint Components
- Cartilage
- Joint Capsule
- Synovium
- Ligaments
- Prevalence of Musculoskeletal Conditions
- Musculoskeletal Conditions In Europe
- Musculoskeletal Conditions In the United States
- Common Musculoskeletal Conditions
- Osteoarthritis
- Osteoporosis
- Bone Fractures
- Ligament Injuries
- Joint Replacement Procedures
- Introduction
- Most Common Procedures
- Knee Reconstruction
- Hip Reconstruction
- Spinal Fusion
- Future Directions in the treatment of Musculoskeletal conditions
- Gene Therapy
- Stem Cell Therapy
CHAPTER THREE: ORTHOPEDIC BIOMATERIALS
- Overview
- Brief History of Orthopedic Biomaterials
- Categories of Orthopedic Biomaterials
- Bone Grafts
- Types of Bone Grafts
- Autografts
- Advantages
- Disadvantages
- Allograft
- Disadvantages
- Xenografts
- Disadvantages
- Allograft Bone Graft Substitutes
- Overview
- Demineralized Bone Matrix
- Types of DBM Products
- Conventional Allograft
- Machined Allograft
- Ceramic-based Bone Graft Substitutes
- Overview
- Types of Materials
- Hydroxyapatites
- Ceramic Coated Joint Implants
- Coralline Hydroxyapatite
- Tricalcium Phosphate
- Calcium Phosphate
- Calcium Sulphate
- Polymer-based Bone Graft Substitutes
- Overview
- Nondegradable Polymers
- Bioabsorbable Polymer Biomaterials
- Polylactic Acid (PLA)
- Polyglycolic Acid (PGA)
- Copolymers
- Factor-based Bone Graft Substitutes
- Overview
- Types of Growth Factors
- Bone Morphogenic Protein (BMP)
- Transforming Growth Factor-Beta (TGF-
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