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Commercial Opportunities from an Aging Population: Epidemiology, market and pipeline analysis across seven major indications

Product Type: Market Research Report Publication Date: Feb 01, 2004
 
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SUMMARY

Commercial Opportunities from an Aging Population: Epidemiology market andpipeline analysis across seven major indications, evaluates the benefits ofmarketing to seniors for the pharmaceutical industry. Globally, the number ofolder people will increase from 606m in 2000 to 1.9bn in 2050 and as a resulthealthcare needs will increase and drugs will be used for longer.

This report analyzes commercial opportunities within the 'gray market' and shows how companies can meet these needs and keep company profits high.Current and future growth prospects are examined for pharmaceutical companies to2008 in seven major indications particularly associated with seniors. These areacute ischemic stroke, Alzheimer' s disease, arthritis, diabetes, male sexualdysfunction, osteoporosis and prostate cancer. Cumulatively, the total value ofthese markets was approximately $42bn in 2002 and this figure is set to risedramatically.

TABLE OF CONTENTS

Executive Summary

Quantifying the 'gray market'  opportunity
Acute ischemic stroke
Alzheimer' s disease
Arthritis
Diabetes
Male sexual dysfunction
Osteoporosis
Prostate cancer

Chapter 1 Quantifying the 'gray market'

opportunity
Summary
Introduction
Drivers of gray market growth
Demographic trends: an aging population
Healthcare needs increase with age
The prevalence of chronic diseases is significantly higher among seniors
Drugs will be used for longer as life expectancy increases
Seniors'  influence on the prescribing process
Exploiting increased contact between seniors and physicians
Harnessing the power of the web to communicate with seniors
Internet use is already promoting patient-physician interaction
Meeting seniors. health information needs
Pharmaceutical industry online initiatives targeting seniors . Novartis.healthandage.com

Chapter 2 Acute ischemic stroke

Summary
Disease overview
Epidemiology
Market analysis: focus on antithrombotics
Activase (alteplase)
Pipeline analysis
Unmet needs in acute therapy
Failure of neuroprotective agents
Are antithrombotics the answer?
Antithrombotics in development for acute ischemic stroke
ReoPro (abciximab)
Retavase (reteplase)

Chapter 3 Alzheimer' s disease

Summary
Disease overview
Epidemiology
Market analysis
Aricept (donepezil)
Exelon (rivastigmine)
Reminyl (galantamine)
Ebixa (memantine)
Late-stage pipeline analysis
Cere (cerebrolysin)
COGNIShunt
NS-2330

Chapter 4 Arthritis

Summary
Disease overview
Epidemiology
Market analysis
Celebrex (celecoxib)
Vioxx (rofecoxib)
Bextra (valdecoxib)
Remicade (infliximab)
Pipeline analysis
Prexige (lumiracoxib)
CDP-870

Chapter 5 Diabetes

Summary
Disease overview
Epidemiology
Market analysis
Class dynamics
Sulfonylureas
Biguanides
Thiazolidinediones
Prandial glucose regulators
Alfa glucosidase inhibitors
Insulins
Monotherapy versus combination therapy
Leading and new products
Avandia (rosiglitazone)
Novolin (insulin)
Humalog (insulin lispro)
Lantus (insulin glargine)
Pipeline analysis
Exubera (inhaled insulin)
AERx insulin Diabetes Management System (inhaled insulin)
Oralin (transoral insulin)
HIM2 (oral insulin)

Chapter 6 Male sexual dysfunction

Summary
Disease overview
Loss of libido
Erectile dysfunction
Priapism
Peyronie.s disease
Premature and delayed ejaculation
Epidemiology
Market analysis
Viagra (sildenafil)
Cialis (tadalafil)
Levitra/Nuviva (vardenafil)
Pipeline analysis
Alibra (alprostadil + prazosin)
Alprox-TD (alprostadil)
Dapoxetine
PNU-83757

Chapter 7 Osteoporosis

Summary
Disease overview
Pathophysiology and etiology
Epidemiology
Methodological difficulties in assessing prevalence
Prevalence of osteoporosis and osteopenia in post-menopausal women
Prevalence of osteoporosis and osteopenia in men
Market analysis
Impact of the Women.s Health Initiative on osteoporosis therapy
Leading and new product sales to 2008
Premarin family (conjugated estrogens)
Fosamax (alendronate)
Actonel (risedronate)
Evista (raloxifene)
Forteo (teriparatide)
Pipeline analysis
Boniva/Bondronat (ibandronate)
Zometa (zoledronate)
Lasofoxifene
Premarin (conjugated estrogens) + bazedoxifene

Chapter 8 Prostate cancer

Summary
Disease overview
Epidemiology
Market analysis
Zoladex (goserelin)
Casodex (bicalutamide)
Lupron (leuprolide)
Pipeline analysis
Plenaxis (abarelix depot)
Atrasentan
Provenge (aberalix depot)

Chapter 9 Appendix

References
Alzheimer.s disease
Male sexual dysfunction
Osteoporosis
Prostate cancer
Index

List of Figures

Figure 1.1: Average annual growth rates of the total population and thepopulation in broad ag groups, by major area, 2000-50 (median variant)
Figure 1.2: The aging female population provides expanding opportunitiesin women.s health
Figure 1.3: Healthcare spend increases with age
Figure 1.4: Life expectancy at birth is rising
Figure 1.5: Seniors visit physicians more frequently than their youngercounterparts
Figure 1.6: The rate of Internet uptake is greatest among seniors
Figure 1.7: Online seniors are approaching physicians with informationfrom the Internet
Figure 1.8: Online seniors are searching for information on age-relateddiseases
Figure 1.9: Novartis. www.healthandage.com
Figure 2.10: Incidence of ischemic stroke in the seven major markets, 2002
Figure 3.11: Prevalence of Alzheimer.s disease across the seven majormarkets, 2002
Figure 6.12: Prevalence of male sexual dysfunction, 2002 1
Figure 7.13: Prevalence of osteopenia and osteoporosis in thepost-menopausal population across the seven major markets, 2002 1
Figure 7.14: Prevalence of osteopenia and osteoporosis in men aged 50+,2002 1
Figure 8.15: Segmentation of prostate cancer patients among the sevenmajor markets, 2003 1

List of Tables

Table 2.1: Incidence of ischemic stroke in the seven major markets, 2002
Table 2.2: Antithrombotics in development for acute ischemic stroke, 2003
Table 3.3: Prevalence of Alzheimer.s disease across the seven majormarkets, 2002
Table 3.4: Leading and new Alzheimer.s disease product sales, 2001-08
Table 3.5: Late stage Alzheimer.s disease pipeline, 2003
Table 4.6: Leading and new arthritis product sales, 2001-08
Table 4.7: Late-stage arthritis pipeline, 2003
Table 5.8: Prevalence of diabetes in the seven major markets, 2002 1
Table 5.9: Leading and new diabetes product sales, 2001-08 1
Table 5.10: Non-invasive insulin pipeline, 2003 1
Table 6.11: Prevalence of male sexual dysfunction, 2002 (000s) 1
Table 6.12: Prevalence of complete and severe erectile dysfunction in theover 40s, 2002 (000s)
Table 6.13: Global forecasts of leading and innovative erectiledysfunction drugs to 2008
Table 6.14: Male sexual dysfunction pipeline, phase II and above, 2003
Table 7.15: Prevalence of osteopenia and osteoporosis in thepost-menopausal population across the seven major markets, 2002
Table 7.16: Prevalence of osteopenia and osteoporosis in men aged 50+,2002
Table 7.17: Leading and new product sales in the osteoporosis market,2002-08
Table 7.18: Osteoporosis pipeline, phase II and above, 2003
Table 8.19: Prevalence of prostate cancer in the seven major markets, 2003
Table 8.20: Leading prostate cancer product sales, 2001-08
Table 8.21: Late-stage prostate cancer pipeline, 2003


Commercial Opportunities from an Aging Population: Epidemiology, market and pipeline analysis across seven major indications

Publisher: Business Insights

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