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SUMMARY
This is the latest Epigenetics and MicroRNA Diagnostics/Therapeutics Market
Report from Select Biosciences. This report presents an up-to-date and
thorough analysis of the Epigenetics Marketplace based upon our continuing
industry coverage. Epigenetics is undergoing a massive industry expansion and
this report focuses in on the science, market, and therapeutics trends in this
emerging area.
MicroRNAs are an emerging and important component of the epigenetic market
space and therefore Select Biosciences focuses in on the diagnostic and
therapeutics opportunities in this report-these are expanding opportunities
with various companies establishing their positions.
Epigenetics
This report presents an exhaustive analysis of the science behind epigenetics
as well as the therapeutics landscape-the current FDA-approved therapeutics as
well as the trials pipeline. Select Biosciences has also performed proprietary
market surveys to assess the epigenetics market landscape qualitatively and
quantitatively. The overall focus of this report therefore is on the science
and business that is leading to market opportunities and translating into
epigenetic therapeutics. Select Biosciences also presents in this report the
current worldwide pipeline of all the HDAC inhibitors in various stages and
the impact HDAC inhibitors are making in epigenetics-these are important
therapeutics that are impacting epigenetics-based therapeutics.
MicroRNAs
Select Biosciences has extensively characterized the life science research
marketplace for microRNAs in a recently-published market report-MicroRNA 2008.
In the current report, Select Biosciences focuses on the emerging microRNA
landscape for diagnostics and therapeutics. There has been significant
industry activity in this space recently with several new entrants. Select
Biosciences map the market landscape for diagnostics and
therapeutics-characterizing various disease areas potentially impacted by
microRNA diagnostics/therapeutics. Select Biosciences proprietary market
surveys addressed the qualitative and quantitative trends in the microRNA
marketplace in terms of technologies utilized, diagnostics/therapeutics
markets impacted, and quantitative industry metrics-this highly valuable and
recently collected dataset is based on an extensive market analysis performed
by Select Biosciences Industry Analyst Team-all the raw data and analyses
based on the data are presented in the report.
The report provides an up-to-date coverage of the patent applications in
the microRNA space defining the intellectual property (IP) coverage,
especially as they relate to diagnostics and therapeutics.
TABLE OF CONTENTS
Chapter I. Executive Overview of the Space
- What is Epigenetics?
- Epigenetics: An emerging market space
- How Epigenetics modifications affect gene expression
- Cellular pathways disrupted by promoter CpG island hypermethylation
- The various chromatin modifications
- MicroRNAs as an epigenetic controller
- Scope of this report
Chapter II. Biology of Epigenetics
Chapter III. Epigenetics Market Landscape
- Technologies to study epigenetics
- Epigenetics-based therapeutics pipeline
- Primary market survey: Characterizing the epigenetics landscape in
qualitative and quantitative terms
- Emerging trends in the epigenetics marketplace
- Profiles of selected epigenetics diagnostics-focused companies
Chapter IV. Market Landscape-microRNA-based Diagnostics and Therapeutics
- microRNAs in Cancer (Types of cancer, microRNA associations)
- microRNAs associated with diseases other than cancer
- Developmental pathways are also regulated by microRNAs, and these may be
therapeutics targets
- microRNAs that may regulate cancer-related genes
- microRNA expression profiling in human cancers and its significance
- Primary market survey: Characterizing the microRNA landscape in
qualitative and quantitative terms
- Profiles: Selected microRNA diagnostic and therapeutics focused companies
[their business focus,
Appendix I. Research Methodology
Appendix II. Glossary of Terms
Appendix III. IP Filings in the microRNA Space
Appendix IV. Selected Events in the Epigenetics Marketplace
Appendix V. HDAC Inhibitors-R&D Pipeline
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